Isagenix is an active health and wellness MLM/direct-selling company founded in 2002 and headquartered in Gilbert, Arizona. The company sells weight-management systems, protein shakes and bars, cleansing products, collagen and beauty supplements, targeted health supplements, fitness products, and home-care products through online retail and independent Associates. Its Associate opportunity remains active and uses an MLM compensation structure involving personal sales, team volume, downlines, commissions, bonuses, and rank-based incentives.
Isagenix products include nutritional cleansing, nutritional supplements, weight loss products and skin care. Isagenix's vision is "to impact world health and free people from physical and financial pain, and in the process create the largest health-and-wellness company in the world." The company has more than $1 billion in cumulative sales and grew 246% from 2005 to 2009.
The company underwent a major financial restructuring in 2023 that shifted majority ownership to key financial stakeholders and eliminated approximately $130 million in debt. Isagenix's legal and regulatory history includes a $350,000 California Proposition 65 settlement in 2012, a 2020 FTC warning letter over COVID-19 product and earnings claims made by participants, a 2025 DSSRC inquiry over income claims that was administratively closed after Isagenix modified or removed 13 posts, and a distributor-contract dispute involving longtime Associates who had received more than $22.3 million in commissions and bonuses.
Becoming an Isagenix Associate requires the purchase of a $39.00 Associate support system with the initial enrollment. The Associate support system includes a personalized website and back office. Optional Product Introduction Paks can also be purchased. Isagenix has a binary compensation plan. All Associates are eligible to earn retail profits and product introduction bonuses. In order to participate fully in the compensation plan, Associates need to be active and have at least one active associate on each of their left and right sales teams at any time within the prior 30 days. Eligible Isagenix Associates can earn team bonuses, executive matching team bonuses, and benefits such as product discounts, healthcare benefits, and more.
Isagenix is a member of the DSA.